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Mousinho-Ribeiro,Rita de Cassia; Pante-de-Sousa,Gabriella; Santos,Eduardo José Melo dos; Guerreiro,João Farias. |
The distribution of b-globin gene haplotypes was studied in 209 Amerindians from eight tribes of the Brazilian Amazon: Asurini from Xingú, Awá-Guajá, Parakanã, Urubú-Kaapór, Zoé, Kayapó (Xikrin from the Bacajá village), Katuena, and Tiriyó. Nine different haplotypes were found, two of which (n. 11 and 13) had not been previously identified in Brazilian indigenous populations. Haplotype 2 (+ - - - -) was the most common in all groups studied, with frequencies varying from 70% to 100%, followed by haplotype 6 (- + + - +), with frequencies between 7% and 18%. The frequency distribution of the b-globin gene haplotypes in the eighteen Brazilian Amerindian populations studied to date is characterized by a reduced number of haplotypes (average of 3.5) and low... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: DNA polymorphisms; Brazilian Amerindians; Genetic diversity. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572003000300002 |
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Pante-de-Sousa,Gabriella; Mousinho-Ribeiro,Rita de Cassia; Santos,Eduardo José Melo dos; Zago,Marco Antonio; Guerreiro,João Farias. |
We analyzed DNA polymorphisms in the <FONT FACE="Symbol">b</font>-globin gene cluster of 30 sickle cell anemia patients from Belém, the capital city of the State of Pará, in order to investigate the origin of the <FONT FACE="Symbol">b</font>S mutation. Sixty-seven percent of the <FONT FACE="Symbol">b</font>S chromosomes were Bantu type, 30% were Benin type, and 3% were Senegal type. The origin of the <FONT FACE="Symbol">b</font>S mutation in this population, estimated on the basis of <FONT FACE="Symbol">b</font>S-linked haplotypes, contradicts the historical records of direct slave trade from Africa to the northern region of Brazil. Historical records indicate a lower percentage of people from... |
Tipo: Info:eu-repo/semantics/article |
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Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47571998000400001 |
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